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FAM168A | Protein FAM168A; In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels (244 aa) | |||
RPL18A | Ribosomal protein L18a (176 aa) | |||
RPL19 | Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family (196 aa) | |||
RPS12 | Ribosomal protein S12 (132 aa) | |||
RPS16 | Ribosomal protein S16 (146 aa) | |||
EEFSEC | Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP (596 aa) | |||
RPL35 | 60S ribosomal protein L35; Component of the large ribosomal subunit (123 aa) | |||
RPL8 | 60S ribosomal protein L8; Component of the large ribosomal subunit (257 aa) | |||
RPL3L | Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family (407 aa) | |||
RPS11 | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa) | |||
RPS27A | Ubiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...] (156 aa) | |||
RPL37 | 60S ribosomal protein L37; Binds to the 23S rRNA; L ribosomal proteins (97 aa) | |||
RPS3 | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...] (259 aa) | |||
RPL39L | Ribosomal protein L39 like; Belongs to the eukaryotic ribosomal protein eL39 family (51 aa) | |||
RPS23 | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa) | |||
RPL10L | 60S ribosomal protein L10-like; May play a role in compensating for the inactivated X- linked gene during spermatogenesis; L ribosomal proteins (214 aa) | |||
RPS9 | Ribosomal protein S9 (194 aa) | |||
RPL13 | Ribosomal protein L13 (211 aa) | |||
RPL15 | Ribosomal protein L15 (204 aa) | |||
RPL38 | Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family (70 aa) | |||
RPL4 | L ribosomal proteins (427 aa) | |||
RPS15A | Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family (130 aa) | |||
RPLP2 | 60S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis; L ribosomal proteins (115 aa) | |||
RPS27L | Ribosomal protein S27 like; Belongs to the eukaryotic ribosomal protein eS27 family (84 aa) | |||
SECISBP2 | Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB (854 aa) | |||
ATXN7L3 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa) |