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| DCN | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans (359 aa) | |||
| MXRA5 | Matrix-remodeling-associated protein 5; In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli; I-set domain containing (2828 aa) | |||
| SGTA | Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Co-chaperone that binds misfolded and hydrophobic patches-containing client proteins in the cytosol. Mediates their targeting to the endoplasmic reticulum but also regulates their sorting to the proteasome when targeting fails. Functions in tail-anchored/type II transmembrane proteins membrane insertion constituting with ASNA1 and the BAG6 complex a targeting module. Probably functions upstream of the BAG6 complex and ASNA1, binding more rapidly the transmembrane domain of newly synthesized proteins. It is also inv [...] (313 aa) | |||
| ISLR | Immunoglobulin superfamily containing leucine rich repeat; I-set domain containing (428 aa) | |||
| OGN | Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2; Small leucine rich repeat proteoglycans (298 aa) | |||
| SLIT1 | Slit homolog 1 protein; Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb (1534 aa) | |||
| TMTC3 | Transmembrane and TPR repeat-containing protein 3; Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response; Tetratricopeptide repeat domain containing (914 aa) | |||
| LUM | Lumican; Small leucine rich repeat proteoglycans; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily (338 aa) | |||
| KERA | Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix; Small leucine rich repeat proteoglycans (352 aa) | |||
| IGSF10 | Immunoglobulin superfamily member 10; Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons) (By similarity). May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity); I-set domain containing (2623 aa) | |||
| LRRC3 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 (257 aa) | |||
| TMTC2 | Transmembrane and tetratricopeptide repeat containing 2 (836 aa) | |||
| BGN | Biglycan; May be involved in collagen fiber assembly; Small leucine rich repeat proteoglycans (368 aa) | |||
| SLIT3 | Slit homolog 3 protein; May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors (1530 aa) | |||
| GPR125 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (1321 aa) | |||
| TTC33 | Tetratricopeptide repeat domain containing (262 aa) | |||
| NYX | Nyctalopin (481 aa) | |||
| TMTC4 | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family (760 aa) | |||
| PRELP | Prolargin; May anchor basement membranes to the underlying connective tissue; Small leucine rich repeat proteoglycans (382 aa) | |||
| ECM2 | Extracellular matrix protein 2; Promotes matrix assembly and cell adhesiveness (699 aa) | |||
| COL15A1 | Collagen alpha-1(XV) chain; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle; Collagen proteoglycans (1388 aa) | |||
| LRRC3C | Leucine-rich repeat-containing protein 3C; Leucine rich repeat containing 3C (275 aa) | |||
| SGTB | Small glutamine-rich tetratricopeptide repeat-containing protein beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity; Tetratricopeptide repeat domain containing (304 aa) | |||
| LRRC3B | Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B (259 aa) | |||
| SLIT2 | Slit homolog 2 protein; Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they [...] (1529 aa) | |||
| ASNA1 | ATPase ASNA1; ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa) | |||
