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  • 11.0 [archived version]
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MRPL44 MRPL44 MRPS35 MRPS35 MAGEC1 MAGEC1 MRPL34 MRPL34 MRPS9 MRPS9 SOD2 SOD2 MRPS5 MRPS5 MRPL49 MRPL49 MRPS16 MRPS16 MRPL32 MRPL32 MRPS10 MRPS10 MRPS7 MRPS7 DICER1 DICER1 DAP3 DAP3 MRPL27 MRPL27 HADHB HADHB ACAA2 ACAA2 DROSHA DROSHA RPS5 RPS5 RPS11 RPS11 RPS20 RPS20 ACAT1 ACAT1 ACAA1 ACAA1 ALAS1 ALAS1 ECHDC2 ECHDC2 ACAT2 ACAT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPS10Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family (201 aa)
MRPS35Mitochondrial ribosomal protein S35 (323 aa)
MRPL32Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
MRPL27Mitochondrial ribosomal protein L27 (148 aa)
MRPS7Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family (242 aa)
MRPL34Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family (92 aa)
MRPL4439S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins (332 aa)
MRPS9Mitochondrial ribosomal protein S9 (396 aa)
ACAT1Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism (427 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa)
MRPS5Mitochondrial ribosomal protein S5 (430 aa)
MRPL49Mitochondrial ribosomal protein L49 (166 aa)
ACAA23-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage (397 aa)
MAGEC1Melanoma-associated antigen C1; MAGE family member C1 (1142 aa)
HADHBhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (474 aa)
ACAA13-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 (424 aa)
ACAT2Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase 2 (397 aa)
DAP328S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family (398 aa)
ECHDC2Enoyl-CoA hydratase domain-containing protein 2, mitochondrial; enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family (292 aa)
MRPS16Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family (137 aa)
ALAS15-aminolevulinate synthase, nonspecific, mitochondrial; 5’-aminolevulinate synthase 1; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family (640 aa)
DROSHARibonuclease 3; Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3’ and 5’ strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Invo [...] (1374 aa)
RPS20Ribosomal protein S20 (142 aa)
DICER1Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3’ overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA- induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, a [...] (1922 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (222 aa)
RPS5Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family (204 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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