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OLFM4 | Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin (510 aa) | |||
TMEM147 | Transmembrane protein 147 (224 aa) | |||
SLC1A1 | Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorptio [...] (524 aa) | |||
GPR128 | Adhesion G-protein coupled receptor G7; Orphan receptor (797 aa) | |||
LAPTM5 | Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family (262 aa) | |||
SLC25A22 | Mitochondrial glutamate carrier 1; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+); Belongs to the mitochondrial carrier (TC 2.A.29) family (323 aa) | |||
PTTG1IP | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation (180 aa) | |||
ZNF395 | Zinc finger protein 395; Plays a role in papillomavirus genes transcription; Zinc fingers C2H2-type (513 aa) | |||
PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation; Belongs to the phospholamban family (52 aa) | |||
LDLRAD1 | Low density lipoprotein receptor class A domain containing 1 (205 aa) | |||
TMEM218 | Transmembrane protein 218; May be involved in ciliary biogenesis or function (115 aa) | |||
GIMAP5 | GTPase IMAP family member 5; Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity); GTPases, IMAP (511 aa) |