26 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MRPS10	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family (201 aa)
	MRPS35	Mitochondrial ribosomal protein S35 (323 aa)
	MRPL32	Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
	MRPL27	Mitochondrial ribosomal protein L27 (148 aa)
	MRPS7	Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family (242 aa)
	MRPL34	Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family (92 aa)
	MRPL4	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
	MRPL44	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins (332 aa)
	MRPS9	Mitochondrial ribosomal protein S9 (396 aa)
	MRPL15	Mitochondrial ribosomal protein L15 (296 aa)
	MRPL3	Mitochondrial ribosomal protein L3 (348 aa)
	MRPS5	Mitochondrial ribosomal protein S5 (430 aa)
	MRPL49	Mitochondrial ribosomal protein L49 (166 aa)
	MRPL13	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa)
	HIBCH	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)
	DAP3	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family (398 aa)
	MRPS2	Mitochondrial ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (296 aa)
	MRPS16	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family (137 aa)
	MRPS15	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family (257 aa)
	MRPL2	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family (305 aa)
	MRPS12	Mitochondrial ribosomal protein S12 (138 aa)
	MRPL36	Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family (103 aa)
	ACADVL	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family (678 aa)
	KIAA0391	Mitochondrial ribonuclease P catalytic subunit; Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and MRPP3, which cleaves tRNA molecules in their 5’-ends. The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5’-ends (583 aa)
	SOD2	Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (222 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family (204 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADVL	HIBCH	ENSP00000438689	ENSP00000352706	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA	0.845
DAP3	HIBCH	ENSP00000357320	ENSP00000352706	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA	0.804
DAP3	MRPL13	ENSP00000357320	ENSP00000306548	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.997
DAP3	MRPL15	ENSP00000357320	ENSP00000260102	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L15	0.997
DAP3	MRPL2	ENSP00000357320	ENSP00000373404	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family	0.996
DAP3	MRPL27	ENSP00000357320	ENSP00000225969	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L27	0.996
DAP3	MRPL3	ENSP00000357320	ENSP00000264995	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L3	0.998
DAP3	MRPL32	ENSP00000357320	ENSP00000223324	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family	0.995
DAP3	MRPL34	ENSP00000357320	ENSP00000252602	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family	0.991
DAP3	MRPL36	ENSP00000357320	ENSP00000423399	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family	0.995
DAP3	MRPL4	ENSP00000357320	ENSP00000253099	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.999
DAP3	MRPL44	ENSP00000357320	ENSP00000258383	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.998
DAP3	MRPL49	ENSP00000357320	ENSP00000279242	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L49	0.997
DAP3	MRPS10	ENSP00000357320	ENSP00000053468	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family	0.999
DAP3	MRPS12	ENSP00000357320	ENSP00000384952	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S12	0.995
DAP3	MRPS15	ENSP00000357320	ENSP00000362208	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family	0.999
DAP3	MRPS16	ENSP00000357320	ENSP00000362036	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.998
DAP3	MRPS2	ENSP00000357320	ENSP00000360850	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family	0.999
DAP3	MRPS35	ENSP00000357320	ENSP00000081029	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S35	0.999
DAP3	MRPS5	ENSP00000357320	ENSP00000272418	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein S5	0.999

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