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| UROD | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (367 aa) | |||
| ICAM1 | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation; CD molecules (532 aa) | |||
| PDCD6 | Programmed cell death protein 6; Calcium sensor that plays a key role in processes such as endoplasmic reticulum (ER)-Golgi vesicular transport, endosomal biogenesis or membrane repair. Acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium- calcium-binding triggers exposure of apolar surface, promoting interaction with different sets of proteins thanks to 3 different hydrophobic pockets, leading to translocation to membranes. Involved in ER-Golgi transport by promoting the association between PDCD6IP and TSG101, thereby b [...] (191 aa) | |||
| ZNF112 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type (913 aa) | |||
| BCL11B | B-cell lymphoma/leukemia 11B; Key regulator of both differentiation and survival of T- lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus. Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T- lymphocytes. Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC- rich response elemen [...] (894 aa) | |||
| NUDT13 | Nucleoside diphosphate-linked moiety X motif 13; Nudix hydrolase family (352 aa) | |||
| ZNF460 | Zinc finger protein 460; May be involved in transcriptional regulation; Zinc fingers C2H2-type (562 aa) | |||
| DPM1 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins; catalytic subunit of the dolichol- phosphate mannose (DPM) synthase complex; Glycosyltransferase family 2 (260 aa) | |||
| SEC31A | Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity); WD repeat domain containing (1220 aa) | |||
| KCNIP1 | Potassium voltage-gated channel interacting protein 1; EF-hand domain containing (241 aa) | |||
| KLF8 | Krueppel-like factor 8; Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK); Belongs to the Sp1 C2H2-type zinc-finger protein family (359 aa) | |||
| IVD | Isovaleryl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase family (426 aa) | |||
| KLHL29 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing (875 aa) | |||
