• Version:
  • 11.0 [archived version]
STRINGSTRING
OSTC OSTC RPL35A RPL35A RPL7 RPL7 RPL19 RPL19 RPS7 RPS7 RPL14 RPL14 RPL8 RPL8 ENSG00000270800 ENSG00000270800 RPL10A RPL10A SRP68 SRP68 RPL18A RPL18A SEC61B SEC61B RPS3 RPS3 RPL36AL RPL36AL RPL37A RPL37A RPL3 RPL3 FAU FAU RPS16 RPS16 RPL31 RPL31 RPL27A RPL27A RPS20 RPS20 SEC61A1 SEC61A1 RPS12 RPS12 RPS27 RPS27 RPS14 RPS14 RPS15 RPS15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPL18ARibosomal protein L18a (176 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SEC61-beta family (96 aa)
RPL19Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family (196 aa)
RPS12Ribosomal protein S12 (132 aa)
SEC61A1Protein transport protein Sec61 subunit alpha isoform 1; Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity); Belongs to the SecY/SEC61-alpha family (476 aa)
RPS16Ribosomal protein S16 (146 aa)
RPL860S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
RPS340S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...] (259 aa)
SRP68Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function (627 aa)
RPS740S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family (194 aa)
RPL760S ribosomal protein L7; Component of the large ribosomal subunit. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (248 aa)
RPL360S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes; L ribosomal proteins (403 aa)
RPL36ALRibosomal protein L36a like (106 aa)
RPL27ARibosomal protein L27a; Belongs to the universal ribosomal protein uL15 family (148 aa)
RPS2740S ribosomal protein S27; Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs; Belongs to the eukaryotic ribosomal protein eS27 family (84 aa)
RPL10A60S ribosomal protein L10a; Component of the large ribosomal subunit (217 aa)
RPL1460S ribosomal protein L14; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL14 family (215 aa)
RPS14Ribosomal protein S14 (151 aa)
RPL31Ribosomal protein L31 (128 aa)
RPL37ARibosomal protein L37a (92 aa)
RPL35A60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site (110 aa)
OSTCOligosaccharyltransferase complex subunit OSTC; May act as substrate-specific component of the N- oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X- Ser/Thr consensus motif in nascent polypeptide chains. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1; Belongs to the OSTC family (171 aa)
RPS20Ribosomal protein S20 (142 aa)
FAUUbiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion (133 aa)
RPS15Ribosomal protein S15 (145 aa)
ENSG00000270800RPS10-NUDT3 readthrough (286 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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