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  • 11.0 [archived version]
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MRAS MRAS NT5DC1 NT5DC1 CYP4B1 CYP4B1 PKLR PKLR RPL15 RPL15 MRPL11 MRPL11 RPL35 RPL35 RPL5 RPL5 RPL27A RPL27A RPL9 RPL9 RPL18 RPL18 MRPL13 MRPL13 RPL23A RPL23A EEF1A2 EEF1A2 RPL8 RPL8 RPL19 RPL19 RPL21 RPL21 MRTO4 MRTO4 RPL31 RPL31 RPL32 RPL32 RPL11 RPL11 RPL37A RPL37A MRPL15 MRPL15 RPL23 RPL23 RPL12 RPL12 RSL24D1 RSL24D1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EEF1A2Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily (463 aa)
RPL19Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family (196 aa)
RPL3560S ribosomal protein L35; Component of the large ribosomal subunit (123 aa)
MRPL15Mitochondrial ribosomal protein L15 (296 aa)
RSL24D1Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity); Belongs to the eukaryotic ribosomal protein eL24 family (163 aa)
RPL860S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
MRASRas-related protein M-Ras; May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway; Belongs to the small GTPase superfamily. Ras family (208 aa)
MRPL13Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa)
MRPL11Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family (192 aa)
RPL15Ribosomal protein L15 (204 aa)
NT5DC15’-nucleotidase domain containing 1 (455 aa)
PKLRPyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family (574 aa)
RPL27ARibosomal protein L27a; Belongs to the universal ribosomal protein uL15 family (148 aa)
RPL2160S ribosomal protein L21; Component of the large ribosomal subunit (160 aa)
RPL1260S ribosomal protein L12; Binds directly to 26S ribosomal RNA (165 aa)
RPL560S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (297 aa)
CYP4B1Cytochrome P450 4B1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (512 aa)
RPL1160S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] (178 aa)
MRTO4mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes (239 aa)
RPL31Ribosomal protein L31 (128 aa)
RPL23A60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family (156 aa)
RPL9L ribosomal proteins (192 aa)
RPL32Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family (135 aa)
RPL37ARibosomal protein L37a (92 aa)
RPL23Ribosomal protein L23 (140 aa)
RPL1860S ribosomal protein L18; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL18 family (188 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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