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PI3 | Elafin; Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis; WAP four-disulfide core domain containing (117 aa) | |||
CSTA | Cystatin-A; This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis; Belongs to the cystatin family (98 aa) | |||
EVPL | Envoplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments; Plakins (2033 aa) | |||
SPRR1B | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage; Belongs to the cornifin (SPRR) family (89 aa) | |||
LCE1D | Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum (114 aa) | |||
RPTN | Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium; EF-hand domain containing (784 aa) | |||
SPRR3 | Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Small proline rich proteins (169 aa) | |||
LCE5A | Late cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (118 aa) | |||
LCE1F | Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum (118 aa) | |||
LCE3C | Late cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (94 aa) | |||
LCE1A | Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum (110 aa) | |||
LCE3A | Late cornified envelope protein 3A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (89 aa) | |||
PPL | Periplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling; Belongs to the plakin or cytolinker family (1756 aa) | |||
LCE1B | Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum (118 aa) | |||
LOR | Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family (312 aa) | |||
LELP1 | Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family (98 aa) | |||
SPRR2G | Small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Small proline rich proteins (73 aa) | |||
SPRR2E | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (72 aa) | |||
SPRR2B | Small proline-rich protein 2B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (72 aa) | |||
SPRR2D | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (72 aa) | |||
SPRR1A | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (89 aa) | |||
IVL | Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family (585 aa) | |||
LCE1E | Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum (118 aa) | |||
LCE4A | Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (99 aa) | |||
LCE2D | Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum (110 aa) | |||
LCE3D | Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (92 aa) |