3 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDHR3	Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (885 aa)
	CXorf38	Uncharacterized protein CXorf38; Chromosome X open reading frame 38 (319 aa)
	NFYC	Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5’- CCAAT-3’ box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors (354 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXorf38	NFYC	ENSP00000330488	ENSP00000396620	Uncharacterized protein CXorf38; Chromosome X open reading frame 38	Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5’- CCAAT-3’ box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors	0.742
NFYC	CXorf38	ENSP00000396620	ENSP00000330488	Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5’- CCAAT-3’ box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors	Uncharacterized protein CXorf38; Chromosome X open reading frame 38	0.742

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