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| DEFB129 | Beta-defensin 129; Has antibacterial activity; Defensins, beta (183 aa) | |||
| DEFB118 | Beta-defensin 118; Has antibacterial activity; Defensins, beta (123 aa) | |||
| DEFA4 | Neutrophil defensin 4; Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production; Defensins, alpha (97 aa) | |||
| DEFA6 | Defensin-6; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1; Defensins, alpha (100 aa) | |||
| DEFB1 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family (68 aa) | |||
| FAM35A | Protein FAM35A; Family with sequence similarity 35 member A (835 aa) | |||
| PRSS1 | Trypsin-1; Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates; Belongs to the peptidase S1 family (247 aa) | |||
| DEFB114 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS- induced reduction of sperm motility in vitro and may protect from LPS-induced lethality; Defensins, beta (69 aa) | |||
| METRNL | Meteorin-like protein; Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates a [...] (311 aa) | |||
| DEFB112 | Beta-defensin 112; Has antibacterial activity; Defensins, beta (113 aa) | |||
| DEFB124 | Beta-defensin 124; Has antibacterial activity; Defensins, beta (71 aa) | |||
| DEFA3 | Neutrophil defensin 3; Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane; Defensins, alpha (94 aa) | |||
| DEFA5 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing; Defensins, alpha (94 aa) | |||
| DEFB108B | Beta-defensin 108B; Has antibacterial activity; Defensins, beta (73 aa) | |||
| DEFB128 | Beta-defensin 128; Has antibacterial activity; Defensins, beta (93 aa) | |||
| DEFB131 | Beta-defensin 131A; Has antibacterial activity (Probable). Upon stimulation with lipoteichoic acid, promotes cytokines and chemokines production and secretion; Belongs to the beta-defensin family (70 aa) | |||
| PRSS3 | Trypsin-3; Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family (304 aa) | |||
| DEFB110 | Beta-defensin 110; Has antibacterial activity; Defensins, beta (67 aa) | |||
| DEFB123 | Beta-defensin 123; Has antibacterial activity; Belongs to the beta-defensin family (67 aa) | |||
| DEFB119 | Defensin beta 119 (88 aa) | |||
| DEFB135 | Beta-defensin 135; Has antibacterial activity; Defensins, beta (77 aa) | |||
| DEFB136 | Beta-defensin 136; Has antibacterial activity; Defensins, beta (78 aa) | |||
| DEFB132 | Beta-defensin 132; Has antibacterial activity; Defensins, beta (95 aa) | |||
| EPHA6 | Ephrin type-A receptor 6; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity) (1130 aa) | |||
| RPL24 | Ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family (157 aa) | |||
| METRN | Meteorin; Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity); Belongs to the meteorin family (293 aa) | |||
