• Version:
  • 11.0 [archived version]
STRINGSTRING
ENSG00000242631 ENSG00000242631 UGGT2 UGGT2 SP3 SP3 SP5 SP5 SEPT3 SEPT3 UGGT1 UGGT1 ZBTB8B ZBTB8B ZNF544 ZNF544 SEP15 SEP15 TUBB4A TUBB4A ZNF143 ZNF143 ZNF462 ZNF462 RDH11 RDH11 ZNF76 ZNF76 ZNF34 ZNF34 ENAM ENAM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UGGT1UDP-glucose-glycoprotein glucosyltransferase 1; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation; UDP-glucose glycoprotein glucosyltransferases (1555 aa)
TUBB4ATubulin beta-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Tubulins (444 aa)
ZNF544Zinc finger protein 544; May be involved in transcriptional regulation; Zinc fingers C2H2-type (715 aa)
ZNF462Zinc finger protein 462; May be involved in transcriptional regulation; Zinc fingers C2H2-type (2506 aa)
SP3Transcription factor Sp3; Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone- induction and house-keeping (781 aa)
SEP15Selenoprotein F; May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity); Belongs to the selenoprotein M/F family (165 aa)
ZNF34Zinc finger protein 34; May be involved in transcriptional regulation; Zinc fingers C2H2-type (560 aa)
ZNF76Zinc finger protein 76; May be involved in transcriptional regulation; Zinc fingers C2H2-type (570 aa)
SP5Transcription factor Sp5; Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo (By similarity); Sp transcription factors (398 aa)
UGGT2UDP-glucose-glycoprotein glucosyltransferase 2; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation (By similarity); Belongs to the glycosyltransferase 8 family (1516 aa)
RDH11Retinol dehydrogenase 11; Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected (318 aa)
ENAMEnamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation (1142 aa)
SEPT3Neuronal-specific septin-3; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family (358 aa)
ZNF143Zinc finger protein 143; Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8; Belongs to the GLI C2H2-type zinc-finger protein family (638 aa)
ENSG00000242631Zinc finger protein 462 (87 aa)
ZBTB8BZinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation; BTB domain containing (495 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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