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NUFIP2 | Nuclear fragile X mental retardation-interacting protein 2; Binds RNA (695 aa) | |||
RPL19 | Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family (196 aa) | |||
MRPS7 | Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family (242 aa) | |||
EIF2S3 | Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...] (472 aa) | |||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2- GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed b [...] (315 aa) | |||
SUB1 | Activated RNA polymerase II transcriptional coactivator p15; General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (127 aa) | |||
MRPL33 | Mitochondrial ribosomal protein L33 (65 aa) | |||
RPS23 | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa) | |||
RPL38 | Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family (70 aa) | |||
ABCF1 | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F (845 aa) | |||
RPS26 | Ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family (115 aa) | |||
CDC5L | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing (802 aa) | |||
RPL11 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] (178 aa) | |||
EIF2S2 | Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] (333 aa) | |||
SPAG6 | Sperm-associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility; Armadillo repeat containing (509 aa) | |||
RPL24 | Ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family (157 aa) | |||
RPS29 | Ribosomal protein S29 (67 aa) | |||
RPL31 | Ribosomal protein L31 (128 aa) | |||
RPL36A | Ribosomal protein L36a (142 aa) | |||
RPL32 | Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family (135 aa) | |||
RPL30 | Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family (115 aa) | |||
RPL18 | 60S ribosomal protein L18; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL18 family (188 aa) | |||
ENSG00000229117 | Ribosomal protein L41; Interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase II alpha by CKII; L ribosomal proteins (25 aa) | |||
RPS28 | Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family (69 aa) | |||
LARP4B | La-related protein 4B; Stimulates mRNA translation; La ribonucleoprotein domain containing (738 aa) | |||
ENSG00000279483 | 60S ribosomal protein L41; Interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase II alpha by CKII; L ribosomal proteins (25 aa) |