node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SLC35A1 | SLC35B3 | ENSP00000358565 | ENSP00000368981 | CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | 0.736 |
SLC35A1 | SLC35C2 | ENSP00000358565 | ENSP00000318960 | CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | 0.609 |
SLC35A1 | SLC35E1 | ENSP00000358565 | ENSP00000470652 | CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily | Solute carrier family 35 member E1; Putative transporter; Solute carriers | 0.471 |
SLC35B3 | SLC35A1 | ENSP00000368981 | ENSP00000358565 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily | 0.736 |
SLC35B3 | SLC35C2 | ENSP00000368981 | ENSP00000318960 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | 0.832 |
SLC35B3 | SLC35E3 | ENSP00000368981 | ENSP00000381089 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | Solute carrier family 35 member E3; Putative transporter; Solute carriers | 0.512 |
SLC35B3 | TMEM234 | ENSP00000368981 | ENSP00000309792 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | Transmembrane protein 234 | 0.567 |
SLC35C2 | SLC35A1 | ENSP00000318960 | ENSP00000358565 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily | 0.609 |
SLC35C2 | SLC35B3 | ENSP00000318960 | ENSP00000368981 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | 0.832 |
SLC35C2 | SLC35E2 | ENSP00000318960 | ENSP00000246421 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | Solute carrier family 35 member E2; Putative transporter; Solute carriers | 0.648 |
SLC35C2 | SLC35E3 | ENSP00000318960 | ENSP00000381089 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | Solute carrier family 35 member E3; Putative transporter; Solute carriers | 0.702 |
SLC35C2 | SLC35F5 | ENSP00000318960 | ENSP00000245680 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | Solute carrier family 35 member F5; Putative solute transporter; Belongs to the SLC35F solute transporter family | 0.446 |
SLC35C2 | SLC35G1 | ENSP00000318960 | ENSP00000400932 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | Solute carrier family 35 member G1; May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell; Solute carriers | 0.479 |
SLC35C2 | TMEM234 | ENSP00000318960 | ENSP00000309792 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | Transmembrane protein 234 | 0.538 |
SLC35E1 | SLC35A1 | ENSP00000470652 | ENSP00000358565 | Solute carrier family 35 member E1; Putative transporter; Solute carriers | CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily | 0.471 |
SLC35E1 | SLC35F5 | ENSP00000470652 | ENSP00000245680 | Solute carrier family 35 member E1; Putative transporter; Solute carriers | Solute carrier family 35 member F5; Putative solute transporter; Belongs to the SLC35F solute transporter family | 0.540 |
SLC35E1 | SLC35G1 | ENSP00000470652 | ENSP00000400932 | Solute carrier family 35 member E1; Putative transporter; Solute carriers | Solute carrier family 35 member G1; May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell; Solute carriers | 0.480 |
SLC35E2 | SLC35C2 | ENSP00000246421 | ENSP00000318960 | Solute carrier family 35 member E2; Putative transporter; Solute carriers | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | 0.648 |
SLC35E2 | SLC35E3 | ENSP00000246421 | ENSP00000381089 | Solute carrier family 35 member E2; Putative transporter; Solute carriers | Solute carrier family 35 member E3; Putative transporter; Solute carriers | 0.647 |
SLC35E2 | SLC35G1 | ENSP00000246421 | ENSP00000400932 | Solute carrier family 35 member E2; Putative transporter; Solute carriers | Solute carrier family 35 member G1; May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell; Solute carriers | 0.623 |