• Version:
  • 11.0 [archived version]
STRINGSTRING
SLC35E2B SLC35E2B SMAGP SMAGP SLC35G1 SLC35G1 SLC35E2 SLC35E2 SLC35E3 SLC35E3 SLC35F5 SLC35F5 SLC35E1 SLC35E1 SLC35C2 SLC35C2 SLC35B3 SLC35B3 SLC35A1 SLC35A1 SLC34A3 SLC34A3 TMEM234 TMEM234 CREB3L1 CREB3L1 UNC50 UNC50
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC35F5Solute carrier family 35 member F5; Putative solute transporter; Belongs to the SLC35F solute transporter family (523 aa)
SLC35E2Solute carrier family 35 member E2; Putative transporter; Solute carriers (266 aa)
TMEM234Transmembrane protein 234 (140 aa)
SLC35C2Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers (394 aa)
UNC50Protein unc-50 homolog; May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA (By similarity) (259 aa)
SLC35A1CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily (337 aa)
SLC35B3Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers (401 aa)
SLC35E3Solute carrier family 35 member E3; Putative transporter; Solute carriers (313 aa)
SLC35G1Solute carrier family 35 member G1; May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell; Solute carriers (365 aa)
SLC34A3Sodium-dependent phosphate transport protein 2C; May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx; Solute carriers (599 aa)
SLC35E1Solute carrier family 35 member E1; Putative transporter; Solute carriers (410 aa)
SMAGPSmall cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation (97 aa)
SLC35E2BSolute carrier family 35 member E2B; Putative transporter; Solute carriers (405 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1; Transcription factor involved in unfolded protein response (UPR). Binds the DNA consensus sequence 5’-GTGXGCXGC-3’. In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nuc [...] (519 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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