• Version:
  • 11.0 [archived version]
STRINGSTRING
TRAPPC3L TRAPPC3L TRAPPC13 TRAPPC13 SPATA22 SPATA22 TRAPPC12 TRAPPC12 TRAPPC8 TRAPPC8 TRAPPC6A TRAPPC6A TRAPPC6B TRAPPC6B BCL2L14 BCL2L14 TRAPPC1 TRAPPC1 TBC1D14 TBC1D14 TRAPPC9 TRAPPC9 TRAPPC10 TRAPPC10 TRAPPC3 TRAPPC3 GLB1 GLB1 TRAPPC5 TRAPPC5 REPS2 REPS2 REPS1 REPS1 TRAPPC2 TRAPPC2 TRAPPC2L TRAPPC2L GSG1 GSG1 LAP3 LAP3 CABS1 CABS1 RAB3IP RAB3IP POSTN POSTN SSX2 SSX2 C11orf68 C11orf68
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAPPC6ATrafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes; Trafficking protein particle complex (173 aa)
LAP3Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family (519 aa)
CABS1Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1 (395 aa)
TRAPPC8Trafficking protein particle complex subunit 8; May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Trafficking protein particle complex (1435 aa)
TRAPPC10Trafficking protein particle complex subunit 10; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TMEM1 family (1259 aa)
TRAPPC2LTrafficking protein particle complex subunit 2-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. Sedlin subfamily (140 aa)
TRAPPC1Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET5 subfamily (145 aa)
GLB1Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans; Belongs to the glycosyl hydrolase 35 family (677 aa)
BCL2L14Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family (327 aa)
TRAPPC12Trafficking protein particle complex subunit 12; Plays an important role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores. May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Tetratricopeptide repeat domain containing (735 aa)
TRAPPC6BTrafficking protein particle complex subunit 6B; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Trafficking protein particle complex (158 aa)
SSX2Synovial sarcoma, X breakpoint 2; SSX family member 2 (223 aa)
REPS2RalBP1-associated Eps domain-containing protein 2; Involved in growth factor signaling through its influence on the Ral signaling pathway; EF-hand domain containing (660 aa)
TRAPPC3LTrafficking protein particle complex subunit 3-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily (181 aa)
POSTNPeriostin; Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity); Gla domain containing (836 aa)
TRAPPC9Trafficking protein particle complex subunit 9; Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the NIBP family (1246 aa)
TBC1D14TBC1 domain family member 14; Negative regulator of starvation-induced autophagosome formation (693 aa)
REPS1RalBP1-associated Eps domain-containing protein 1; May coordinate the cellular actions of activated EGF receptors and Ral-GTPases; EF-hand domain containing (796 aa)
TRAPPC2Trafficking protein particle complex subunit 2; Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. Sedlin subfamily (174 aa)
C11orf68UPF0696 protein C11orf68; Chromosome 11 open reading frame 68; Belongs to the UPF0696 family (293 aa)
GSG1Germ cell-specific gene 1 protein; May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum (339 aa)
TRAPPC13Trafficking protein particle complex 13 (418 aa)
RAB3IPRab-3A-interacting protein; Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface form [...] (476 aa)
SPATA22Spermatogenesis-associated protein 22; Meiosis-specific protein required for homologous recombination in meiosis I (363 aa)
TRAPPC5Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily (188 aa)
TRAPPC3Trafficking protein particle complex subunit 3; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Trafficking protein particle complex (188 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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