26 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MRPL28	Mitochondrial ribosomal protein L28 (256 aa)
	MRPL27	Mitochondrial ribosomal protein L27 (148 aa)
	MRPS7	Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family (242 aa)
	MRPL4	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
	MRPL44	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins (332 aa)
	MRPL15	Mitochondrial ribosomal protein L15 (296 aa)
	MRPL3	Mitochondrial ribosomal protein L3 (348 aa)
	MRPL17	Mitochondrial ribosomal protein L17 (175 aa)
	MRPL16	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family (251 aa)
	MRPL13	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa)
	MRPL38	Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily (380 aa)
	MRPL11	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family (192 aa)
	MRPL40	Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family (206 aa)
	MRPL43	Mitochondrial ribosomal protein L43 (235 aa)
	MRPL9	Mitochondrial ribosomal protein L9 (267 aa)
	MRPL41	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)
	MRPL14	39S ribosomal protein L14, mitochondrial; Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable); Mitochondrial ribosomal proteins (145 aa)
	MRPS15	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family (257 aa)
	MRPL50	Mitochondrial ribosomal protein L50 (158 aa)
	MRPL2	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family (305 aa)
	MRPL19	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family (292 aa)
	MRPL47	Mitochondrial ribosomal protein L47 (250 aa)
	MRPL36	Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family (103 aa)
	MRPS30	Mitochondrial ribosomal protein S30 (439 aa)
	MRPL22	Mitochondrial ribosomal protein L22 (206 aa)
	MRPL42	Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family (142 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MRPL11	MRPL13	ENSP00000308897	ENSP00000306548	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.999
MRPL11	MRPL14	ENSP00000308897	ENSP00000361084	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	39S ribosomal protein L14, mitochondrial; Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable); Mitochondrial ribosomal proteins	0.996
MRPL11	MRPL15	ENSP00000308897	ENSP00000260102	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L15	0.999
MRPL11	MRPL16	ENSP00000308897	ENSP00000300151	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family	0.999
MRPL11	MRPL17	ENSP00000308897	ENSP00000288937	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L17	0.998
MRPL11	MRPL19	ENSP00000308897	ENSP00000377486	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.999
MRPL11	MRPL2	ENSP00000308897	ENSP00000373404	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family	0.999
MRPL11	MRPL22	ENSP00000308897	ENSP00000431040	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L22	0.997
MRPL11	MRPL27	ENSP00000308897	ENSP00000225969	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L27	0.999
MRPL11	MRPL28	ENSP00000308897	ENSP00000199706	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L28	0.994
MRPL11	MRPL3	ENSP00000308897	ENSP00000264995	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L3	0.997
MRPL11	MRPL36	ENSP00000308897	ENSP00000423399	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family	0.998
MRPL11	MRPL38	ENSP00000308897	ENSP00000308275	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily	0.997
MRPL11	MRPL4	ENSP00000308897	ENSP00000253099	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.999
MRPL11	MRPL40	ENSP00000308897	ENSP00000333401	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family	0.998
MRPL11	MRPL41	ENSP00000308897	ENSP00000360498	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins	0.998
MRPL11	MRPL42	ENSP00000308897	ENSP00000449884	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family	0.996
MRPL11	MRPL43	ENSP00000308897	ENSP00000339844	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L43	0.989
MRPL11	MRPL44	ENSP00000308897	ENSP00000258383	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.995
MRPL11	MRPL47	ENSP00000308897	ENSP00000417602	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family	Mitochondrial ribosomal protein L47	0.996

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