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  • 11.0 [archived version]
STRINGSTRING
POTEC POTEC POTED POTED POTEH POTEH ACTL7A ACTL7A ACTB ACTB ACTL7B ACTL7B ACTR1B ACTR1B ACTL9 ACTL9 ACTG2 ACTG2 ACTG1 ACTG1 POTEI POTEI ACTL10 ACTL10 ACTR1A ACTR1A POTEJ POTEJ ACTR10 ACTR10 ACTRT3 ACTRT3 ACTRT1 ACTRT1 ACTA2 ACTA2 ACTA1 ACTA1 SCIN SCIN POTEF POTEF ACTC1 ACTC1 POTEE POTEE TMOD1 TMOD1 TMOD2 TMOD2 LSP1 LSP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMOD2Tropomodulin-2; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity); Tropomodulins (351 aa)
ACTR10Actin related protein 10 homolog; Belongs to the actin family (417 aa)
TMOD1Tropomodulin-1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus; Tropomodulins (359 aa)
ACTR1BBeta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome; Actin related proteins (376 aa)
ACTC1Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family (377 aa)
SCINAdseverin; Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles. Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization [...] (715 aa)
POTEDPOTE ankyrin domain family member D; Belongs to the POTE family (584 aa)
ACTL9Actin-like protein 9; Actin related proteins (416 aa)
ACTL10Actin-like protein 10; Actin related proteins; Belongs to the actin family (245 aa)
ACTRT3Actin related protein T3 (372 aa)
ACTL7AActin-like protein 7A; Actin related proteins; Belongs to the actin family (435 aa)
POTEHPOTE ankyrin domain family member H (545 aa)
ACTBActin, cytoplasmic 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (375 aa)
POTEFPOTE ankyrin domain family member F; In the C-terminal section; belongs to the actin family (1075 aa)
POTECPOTE ankyrin domain family member C (542 aa)
ACTA1Actin, alpha skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (377 aa)
ACTR1AAlpha-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome; Actin related proteins (376 aa)
ACTRT1Actin related protein T1 (376 aa)
ACTL7BActin-like protein 7B; Actin related proteins; Belongs to the actin family (415 aa)
LSP1Lymphocyte-specific protein 1; May play a role in mediating neutrophil activation and chemotaxis (467 aa)
ACTG2Actin, gamma-enteric smooth muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (376 aa)
POTEJPOTE ankyrin domain family member J; In the N-terminal section; belongs to the POTE family (1038 aa)
POTEIPOTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family (1075 aa)
ACTA2Actin, aortic smooth muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family (377 aa)
POTEEPOTE ankyrin domain family member E; In the C-terminal section; belongs to the actin family (1075 aa)
ACTG1Actin, cytoplasmic 2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family (375 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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