• Version:
  • 11.0 [archived version]
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ABCE1 ABCE1 RPS25 RPS25 RPS12 RPS12 RPS23 RPS23 RPS27A RPS27A RPL21 RPL21 ETF1 ETF1 RPS9 RPS9 RPS21 RPS21 RPL37 RPL37 RPL19 RPL19 SEC61B SEC61B RPS26 RPS26 RPS11 RPS11 RPL15 RPL15 RPL8 RPL8 RPL38 RPL38 RPS3A RPS3A RPL22 RPL22 RPS15A RPS15A RPL39 RPL39 RPS17 RPS17 RPS27 RPS27 RPS16 RPS16 RPS7 RPS7 RPL32 RPL32
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SEC61-beta family (96 aa)
RPL19Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family (196 aa)
RPS12Ribosomal protein S12 (132 aa)
RPS16Ribosomal protein S16 (146 aa)
RPL860S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa)
RPS27AUbiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...] (156 aa)
RPL3760S ribosomal protein L37; Binds to the 23S rRNA; L ribosomal proteins (97 aa)
ABCE1ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly; Belongs to the ABC transporter superfamily. ABCE family (599 aa)
RPS2340S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa)
RPS9Ribosomal protein S9 (194 aa)
RPL15Ribosomal protein L15 (204 aa)
RPL38Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family (70 aa)
RPS15ARibosomal protein S15a; Belongs to the universal ribosomal protein uS8 family (130 aa)
RPS740S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family (194 aa)
RPS21Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family (83 aa)
RPL2160S ribosomal protein L21; Component of the large ribosomal subunit (160 aa)
RPS17Ribosomal protein S17 (135 aa)
RPS3A40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3; Belongs to the eukaryotic ribosomal protein eS1 family (264 aa)
RPL22Ribosomal protein L22; Belongs to the eukaryotic ribosomal protein eL22 family (128 aa)
RPS26Ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family (115 aa)
ETF1Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (437 aa)
RPL39Ribosomal protein L39; Belongs to the eukaryotic ribosomal protein eL39 family (51 aa)
RPS2740S ribosomal protein S27; Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs; Belongs to the eukaryotic ribosomal protein eS27 family (84 aa)
RPL32Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family (135 aa)
RPS25Ribosomal protein S25 (125 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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