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NR3C1 | Glucocorticoid receptor; Isoform Alpha-D3- Has lowest transcriptional activation activity of all isoforms created by alternative initiation. Has transcriptional repression activity; Nuclear hormone receptors (778 aa) | |||
CCDC83 | Coiled-coil domain containing 83 (444 aa) | |||
ACAD8 | Isobutyryl-CoA dehydrogenase, mitochondrial; Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Plays a role in transcriptional coactivation within the ARC complex; Acyl-CoA dehydrogenase family (415 aa) | |||
FAM161B | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family (710 aa) | |||
KLHL15 | Kelch-like protein 15; Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex. Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PPP2R5B for ubiquitination and subsequent proteasomal degradation, thus promoting exchange with other regulatory subunits. Acts as an adapter for CUL3 to target the DNA- end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation. Through the regulation of RBBP8/CtIP protein turnover, plays a key role in DNA damage response, favoring DNA double-strand repair through [...] (604 aa) |