• Version:
  • 11.0 [archived version]
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RPL27 RPL27 RPS3A RPS3A RPS11 RPS11 RPS6 RPS6 RPS2 RPS2 RPS26 RPS26 RPL10A RPL10A RPL4 RPL4 RPL15 RPL15 RPS23 RPS23 RPL8 RPL8 RPS9 RPS9 RPS16 RPS16 RPS8 RPS8 RPL9 RPL9 RPL31 RPL31 RPL37A RPL37A RPL34 RPL34 RPL7A RPL7A RPS14 RPS14 RPL23 RPL23 RPL12 RPL12 RPS13 RPS13 RPS4X RPS4X RPS3 RPS3 CDC5L CDC5L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS16Ribosomal protein S16 (146 aa)
RPL860S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa)
RPS340S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...] (259 aa)
RPS2340S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa)
RPS9Ribosomal protein S9 (194 aa)
RPL15Ribosomal protein L15 (204 aa)
RPL4L ribosomal proteins (427 aa)
RPS2Ribosomal protein S2 (293 aa)
RPS3A40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3; Belongs to the eukaryotic ribosomal protein eS1 family (264 aa)
RPS26Ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family (115 aa)
RPL1260S ribosomal protein L12; Binds directly to 26S ribosomal RNA (165 aa)
CDC5LCell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing (802 aa)
RPL7ARibosomal protein L7a (266 aa)
RPS4XRibosomal protein S4, X-linked; Belongs to the eukaryotic ribosomal protein eS4 family (263 aa)
RPL10A60S ribosomal protein L10a; Component of the large ribosomal subunit (217 aa)
RPS640S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; S ribosomal proteins (249 aa)
RPL3460S ribosomal protein L34; Component of the large ribosomal subunit (117 aa)
RPS8Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family (208 aa)
RPS14Ribosomal protein S14 (151 aa)
RPL31Ribosomal protein L31 (128 aa)
RPL9L ribosomal proteins (192 aa)
RPL37ARibosomal protein L37a (92 aa)
RPL23Ribosomal protein L23 (140 aa)
RPS13Ribosomal protein S13 (151 aa)
RPL2760S ribosomal protein L27; Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (136 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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