• Version:
  • 11.0 [archived version]
STRINGSTRING
LLPH LLPH MAGEB10 MAGEB10 SRPK3 SRPK3 ZC3HAV1 ZC3HAV1 RPL30 RPL30 LYAR LYAR AURKAIP1 AURKAIP1 RPS8 RPS8 CNBP CNBP NFIC NFIC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZC3HAV1Zinc finger CCCH-type antiviral protein 1; Antiviral protein which inhibits the replication of viruses by recruiting the cellular RNA degradation machineries to degrade the viral mRNAs. Binds to a ZAP-responsive element (ZRE) present in the target viral mRNA, recruits cellular poly(A)- specific ribonuclease PARN to remove the poly(A) tail, and the 3’- 5’ exoribonuclease complex exosome to degrade the RNA body from the 3’-end. It also recruits the decapping complex DCP1-DCP2 through RNA helicase p72 (DDX17) to remove the cap structure of the viral mRNA to initiate its degradation from t [...] (902 aa)
LLPHProtein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission (129 aa)
AURKAIP1Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation (199 aa)
LYARCell growth-regulating nucleolar protein; Zinc fingers C2HC-type (379 aa)
SRPK3SRSF protein kinase 3; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity) (567 aa)
MAGEB10Melanoma-associated antigen B10; MAGE family member B10 (347 aa)
RPS8Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family (208 aa)
NFICNuclear factor 1 C-type; Recognizes and binds the palindromic sequence 5’- TTGGCNNNNNGCCAA-3’ present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication; Belongs to the CTF/NF-I family (508 aa)
CNBPCellular nucleic acid-binding protein; Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression; Ring finger proteins (179 aa)
RPL30Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family (115 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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