|
Your Input:
|
||||
| KRT20 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity); Keratins, type I (424 aa) | |||
| TDRD1 | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] (1189 aa) | |||
| KRT5 | Keratin, type II cytoskeletal 5; Keratins, type II (590 aa) | |||
| KRT1 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK; Keratins, type II (644 aa) | |||
| KRT75 | Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle (551 aa) | |||
| KRT6C | Keratin, type II cytoskeletal 6C; Keratins, type II; Belongs to the intermediate filament family (564 aa) | |||
| KRT6B | Keratin, type II cytoskeletal 6B; Keratins, type II; Belongs to the intermediate filament family (564 aa) | |||
| PRPH | Peripherin; Class-III neuronal intermediate filament protein (470 aa) | |||
| KRT85 | Keratin, type II cuticular Hb5; Keratins, type II (507 aa) | |||
| KRT84 | Keratin, type II cuticular Hb4; Keratins, type II (600 aa) | |||
| KRT82 | Keratin, type II cuticular Hb2; Keratins, type II (513 aa) | |||
| MIB1 | E3 ubiquitin-protein ligase MIB1; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF- induced apoptosis (By similarity). Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits [...] (1006 aa) | |||
| KRT24 | Keratin, type I cytoskeletal 24; Keratins, type I (525 aa) | |||
| KRT71 | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (523 aa) | |||
| KRT83 | Keratin, type II cuticular Hb3; Keratins, type II (493 aa) | |||
| KRT72 | Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable) (511 aa) | |||
| KRT78 | Keratin, type II cytoskeletal 78; Keratins, type II (520 aa) | |||
| KRT73 | Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable) (540 aa) | |||
| KRT79 | Keratin, type II cytoskeletal 79; Keratins, type II; Belongs to the intermediate filament family (535 aa) | |||
| SQSTM1 | Sequestosome-1; Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Along with WDFY3, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures). Along with SQSTM1, required to recruit ubiquitinated proteins to PML bodies in the nucleus. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate sign [...] (440 aa) | |||
| KRT80 | Keratin, type II cytoskeletal 80; Keratins, type II (452 aa) | |||
| NBR1 | Next to BRCA1 gene 1 protein; Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets; Zinc fingers ZZ-type (966 aa) | |||
| KRT3 | Keratin, type II cytoskeletal 3; Keratins, type II (628 aa) | |||
| MIB2 | E3 ubiquitin-protein ligase MIB2; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors; Ankyrin repeat domain containing (1070 aa) | |||
| KRT4 | Keratin, type II cytoskeletal 4; Keratins, type II; Belongs to the intermediate filament family (520 aa) | |||
| KRT8 | Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Keratins, type II (511 aa) | |||
