• Version:
  • 11.0 [archived version]
STRINGSTRING
SERTAD3 SERTAD3 CRYL1 CRYL1 C4orf6 C4orf6 SPG11 SPG11 RAB26 RAB26 AP5M1 AP5M1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C4orf6Uncharacterized protein encoded by LINC01587; Chromosome 4 open reading frame 6 (93 aa)
RAB26Ras-related protein Rab-26; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a rol [...] (256 aa)
AP5M1AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed-18395520, it may play a role in cell death; Belongs to the adaptor complexes medium subunit family (490 aa)
SPG11Spatacsin; May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport (2443 aa)
CRYL1Lambda-crystallin homolog; Crystallin lambda 1 (319 aa)
SERTAD3SERTA domain-containing protein 3; Strong transcriptional coactivator (196 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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