• Version:
  • 11.0 [archived version]
STRINGSTRING
RAF1 RAF1 MAP2K1 MAP2K1 ENSG00000276345 ENSG00000276345 PEBP4 PEBP4 MRPS2 MRPS2 ENSG00000273155 ENSG00000273155 MRPS5 MRPS5 MRPL17 MRPL17 MRPS34 MRPS34 MRPL46 MRPL46 MRPL36 MRPL36 MRPL27 MRPL27 MRPS15 MRPS15 MRPS10 MRPS10 MRPL43 MRPL43 MRPL40 MRPL40 MRPL49 MRPL49 RPL23L RPL23L MRPL19 MRPL19 MRPL10 MRPL10 MRPL55 MRPL55 MRPS35 MRPS35 MRPL30 MRPL30 MRPL2 MRPL2 MRPL32 MRPL32 MRPS21 MRPS21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPS10Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family (201 aa)
MRPS35Mitochondrial ribosomal protein S35 (323 aa)
MRPS3428S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation (225 aa)
MRPL32Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
MRPL27Mitochondrial ribosomal protein L27 (148 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kina [...] (648 aa)
PEBP4Phosphatidylethanolamine-binding protein 4; Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization; Belongs to the phosphatidylethanolamine-binding protein family (227 aa)
MRPS5Mitochondrial ribosomal protein S5 (430 aa)
MRPL49Mitochondrial ribosomal protein L49 (166 aa)
MRPL17Mitochondrial ribosomal protein L17 (175 aa)
MRPL10Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family (271 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa)
MRPL46Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family (279 aa)
MRPL40Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family (206 aa)
MRPL30Mitochondrial ribosomal protein L30 (161 aa)
MRPL43Mitochondrial ribosomal protein L43 (235 aa)
MRPS2Mitochondrial ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (296 aa)
MRPS15Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family (257 aa)
MRPL2Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family (305 aa)
MRPL19Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family (292 aa)
RPL23LMitochondrial ribosomal protein L23 (153 aa)
ENSG00000273155annotation not available (131 aa)
MRPL55Mitochondrial ribosomal protein L55 (164 aa)
MRPL36Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family (103 aa)
MRPS21Mitochondrial ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family (87 aa)
ENSG00000276345Mitochondrial ribosomal protein L23 (153 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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