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  • 11.0 [archived version]
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GFM2 GFM2 MRPS34 MRPS34 MRPL4 MRPL4 MRPL34 MRPL34 MRPL51 MRPL51 MRPS18B MRPS18B MRPS25 MRPS25 MRPS7 MRPS7 MRPL44 MRPL44 MRPS35 MRPS35 MRPL49 MRPL49 MRPS10 MRPS10 MRPS28 MRPS28 PTCD3 PTCD3 MRPL27 MRPL27 ERAL1 ERAL1 MRPL32 MRPL32 MTIF2 MTIF2 MRPS36 MRPS36 MRPL3 MRPL3 MRPL10 MRPL10 MRPL15 MRPL15 MRPS18C MRPS18C MRPL28 MRPL28 MRPL33 MRPL33 MRPL53 MRPL53
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPS10Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family (201 aa)
MRPS35Mitochondrial ribosomal protein S35 (323 aa)
MRPS3428S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation (225 aa)
MRPL28Mitochondrial ribosomal protein L28 (256 aa)
MRPL32Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
MRPL27Mitochondrial ribosomal protein L27 (148 aa)
MRPL51Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family (128 aa)
MRPS7Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family (242 aa)
MRPL34Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family (92 aa)
MRPL4Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
MRPS25Mitochondrial ribosomal protein S25 (173 aa)
PTCD3Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation (689 aa)
ERAL1GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (437 aa)
MRPS36Mitochondrial ribosomal protein S36 (103 aa)
MRPL53Mitochondrial ribosomal protein L53 (112 aa)
MRPL4439S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins (332 aa)
MRPS18BMitochondrial ribosomal protein S18B; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily (258 aa)
MRPL15Mitochondrial ribosomal protein L15 (296 aa)
MTIF2Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily (727 aa)
MRPL3Mitochondrial ribosomal protein L3 (348 aa)
MRPS28Mitochondrial ribosomal protein S28; Belongs to the bacterial ribosomal protein bS1 family (187 aa)
MRPL49Mitochondrial ribosomal protein L49 (166 aa)
MRPL10Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family (271 aa)
MRPS18CMitochondrial ribosomal protein S18C (142 aa)
MRPL33Mitochondrial ribosomal protein L33 (65 aa)
GFM2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily (779 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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