• Version:
  • 11.0 [archived version]
STRINGSTRING
GNRH1 GNRH1 BCL7A BCL7A EMC4 EMC4 EMC3 EMC3 KCNK16 KCNK16 TRDN TRDN EMC1 EMC1 EMC6 EMC6 UBQLN2 UBQLN2 MMGT1 MMGT1 EMC9 EMC9 EMC10 EMC10 EMC2 EMC2 EMC7 EMC7 KRT6A KRT6A EMC8 EMC8 HSCB HSCB SLC18A1 SLC18A1 NDUFA9 NDUFA9 FAM186B FAM186B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSCBIron-sulfur cluster co-chaperone protein HscB, mitochondrial; Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria; Belongs to the HscB family (235 aa)
EMC2ER membrane protein complex subunit 2; Tetratricopeptide repeat domain containing (297 aa)
EMC3ER membrane protein complex subunit 3 (261 aa)
EMC8ER membrane protein complex subunit 8 (210 aa)
EMC7ER membrane protein complex subunit 7 (242 aa)
FAM186BProtein FAM186B; Family with sequence similarity 186 member B (893 aa)
NDUFA9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits (377 aa)
EMC4ER membrane protein complex subunit 4; May mediate anti-apoptotic activity (183 aa)
GNRH1Progonadoliberin-1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Endogenous ligands (92 aa)
MMGT1Membrane magnesium transporter 1; Mediates Mg(2+) transport; Belongs to the membrane magnesium transporter (TC 1.A.67) family (131 aa)
EMC10ER membrane protein complex subunit 10; Belongs to the EMC10 family (262 aa)
UBQLN2Ubiquilin-2; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and the endoplasmic reticulum- associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its interaction with ER-localized proteins FAF2/UBXD8 and HERPUD1 and may form [...] (624 aa)
KRT6AKeratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair; Belongs to the intermediate filament family (564 aa)
EMC6ER membrane protein complex subunit 6; Belongs to the EMC6 family (110 aa)
SLC18A1Chromaffin granule amine transporter; Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells; Belongs to the major facilitator superfamily. Vesicular transporter family (525 aa)
KCNK16Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K (322 aa)
EMC9ER membrane protein complex subunit 9 (208 aa)
EMC1ER membrane protein complex subunit 1; Belongs to the EMC1 family (993 aa)
TRDNTriadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact (By similarity). Required for normal skeletal muscle strength. Plays a role in excitation- contraction coupling in the heart and in regulating the rate of heart beats (286 aa)
BCL7AB-cell CLL/lymphoma 7 protein family member A; BCL tumor suppressor 7A; BAF complex (231 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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