• Version:
  • 11.0 [archived version]
STRINGSTRING
ZKSCAN5 ZKSCAN5 PPCDC PPCDC ZNF197 ZNF197 ZSCAN30 ZSCAN30 ZKSCAN8 ZKSCAN8 ZNF263 ZNF263 ZNF446 ZNF446 ZNF444 ZNF444 ZSCAN20 ZSCAN20 ZNF232 ZNF232 ZBED9 ZBED9 ZNF213 ZNF213 ZNF397 ZNF397 ZSCAN32 ZSCAN32 ZKSCAN4 ZKSCAN4 DCAF10 DCAF10 PGBD1 PGBD1 ZSCAN21 ZSCAN21 SCAND1 SCAND1 ZNF24 ZNF24 ZKSCAN1 ZKSCAN1 ZKSCAN3 ZKSCAN3 SIN3A SIN3A ZNF174 ZNF174 SIN3B SIN3B WDR59 WDR59
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF263Zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family (683 aa)
ZNF232Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing (444 aa)
PGBD1PiggyBac transposable element-derived protein 1; Scavenger receptor cysteine rich domain containing; DNA transposon derived genes (809 aa)
ZNF24Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family (368 aa)
WDR59GATOR complex protein WDR59; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1; Belongs to the WD repeat WDR59 family (974 aa)
ZNF174Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family (407 aa)
ZSCAN21Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing (473 aa)
ZKSCAN1Zinc finger protein with KRAB and SCAN domains 1; May be involved in transcriptional regulation; SCAN domain containing (563 aa)
ZNF397Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor; SCAN domain containing (534 aa)
ZKSCAN8Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; SCAN domain containing (578 aa)
ZNF444Zinc finger protein 444; Transcriptional regulator. Binds to the 5’-flanking critical region of the SCARF1 promoter; Belongs to the krueppel C2H2-type zinc-finger protein family (327 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase; Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4’- phosphopantotheine (204 aa)
ZSCAN20Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Myb/SANT domain containing (1043 aa)
SCAND1SCAN domain-containing protein 1; May regulate transcriptional activity; SCAN domain containing (179 aa)
ZKSCAN3Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5’-[GT][AG][AGT]GGGG-3’ and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas; SCAN domain containing (538 aa)
ZKSCAN4Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family (545 aa)
DCAF10DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors (559 aa)
SIN3BPaired amphipathic helix protein Sin3b; Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression (1162 aa)
ZKSCAN5Zinc finger protein with KRAB and SCAN domains 5; May be involved in transcriptional regulation; SCAN domain containing (839 aa)
SIN3APaired amphipathic helix protein Sin3a; Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates wit [...] (1273 aa)
ZNF197Zinc finger protein 197; May be involved in transcriptional regulation; SCAN domain containing (1029 aa)
ZSCAN32Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (697 aa)
ZNF213Zinc finger protein 213; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (459 aa)
ZSCAN30Zinc finger and SCAN domain-containing protein 30; May be involved in transcriptional regulation; SCAN domain containing (494 aa)
ZBED9SCAN domain-containing protein 3; Zinc finger BED-type containing 9; SCAN domain containing (1325 aa)
ZNF446Zinc finger protein 446; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (450 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]