4 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

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Your Input:
	VPREB3	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing (123 aa)
	IGLL1	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing (213 aa)
	VPREB1	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules (145 aa)
	IGHV3-11	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...] (96 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGHV3-11	IGLL1	ENSP00000478725	ENSP00000329312	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...]	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing	0.903
IGHV3-11	VPREB1	ENSP00000478725	ENSP00000385361	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...]	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules	0.934
IGHV3-11	VPREB3	ENSP00000478725	ENSP00000248948	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...]	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing	0.900
IGLL1	IGHV3-11	ENSP00000329312	ENSP00000478725	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...]	0.903
IGLL1	VPREB1	ENSP00000329312	ENSP00000385361	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules	0.998
IGLL1	VPREB3	ENSP00000329312	ENSP00000248948	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing	0.973
VPREB1	IGHV3-11	ENSP00000385361	ENSP00000478725	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...]	0.934
VPREB1	IGLL1	ENSP00000385361	ENSP00000329312	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing	0.998
VPREB1	VPREB3	ENSP00000385361	ENSP00000248948	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing	0.465
VPREB3	IGHV3-11	ENSP00000248948	ENSP00000478725	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing	Immunoglobulin heavy variable 3-11; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which [...]	0.900
VPREB3	IGLL1	ENSP00000248948	ENSP00000329312	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing	Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development; C1-set domain containing	0.973
VPREB3	VPREB1	ENSP00000248948	ENSP00000385361	Pre-B lymphocyte protein 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells; V-set domain containing	Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation; CD molecules	0.465

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