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IBSP | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment; SIBLING family (317 aa) | |||
CCDC170 | Coiled-coil domain containing 170 (715 aa) | |||
CCNH | Cyclin-H; Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout [...] (323 aa) | |||
CTCF | Transcriptional repressor CTCF; Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by ac [...] (727 aa) | |||
RNF113B | Ring finger protein 113B (322 aa) | |||
MIS18A | Protein Mis18-alpha; Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis (233 aa) | |||
ZNF565 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type (499 aa) | |||
ZNF408 | Zinc finger protein 408; May be involved in transcriptional regulation; PR/SET domain family (720 aa) | |||
ZBTB2 | Zinc finger and BTB domain-containing protein 2; May be involved in transcriptional regulation; BTB domain containing (514 aa) | |||
ZNF662 | Zinc finger protein 662; Zinc fingers C2H2-type (452 aa) | |||
ZFP91 | E3 ubiquitin-protein ligase ZFP91; Atypical E3 ubiquitin-protein ligase that mediates ’Lys- 63’-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non- canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis; Belongs to the krueppel C2H2-type zinc-finger protein family (570 aa) | |||
RNF113A | RING finger protein 113A; Spliceosomal Bact complex; Ring finger proteins (343 aa) | |||
ZBTB40 | Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation; BTB domain containing (1239 aa) | |||
RBM17 | Splicing factor 45; Splice factor that binds to the single-stranded 3’AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia; G-patch domain containing (401 aa) | |||
SP7 | Transcription factor Sp7; Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity) (431 aa) |