• Version:
  • 11.0 [archived version]
STRINGSTRING
TSFM TSFM MRPL45 MRPL45 MRPL4 MRPL4 MRPL38 MRPL38 MTIF2 MTIF2 MRPL52 MRPL52 ICT1 ICT1 MRPL37 MRPL37 MRPL51 MRPL51 GFM2 GFM2 RPL23L RPL23L MRPL50 MRPL50 MRPL44 MRPL44 MRPS34 MRPS34 TUFM TUFM MRPL1 MRPL1 MRPL47 MRPL47 MRPS36 MRPS36 MRPL41 MRPL41 MRPS30 MRPS30 MRPL21 MRPL21 MRPL40 MRPL40 MRPL42 MRPL42 MRPL24 MRPL24 MRRF MRRF ERAL1 ERAL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPS3428S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation (225 aa)
MRPL51Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family (128 aa)
MRPL4Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
ERAL1GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (437 aa)
MRPS36Mitochondrial ribosomal protein S36 (103 aa)
MRPL4439S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins (332 aa)
MTIF2Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily (727 aa)
GFM2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily (779 aa)
ICT1Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
MRPL38Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily (380 aa)
TSFMElongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome; Belongs to the EF-Ts family (346 aa)
MRPL1Mitochondrial ribosomal protein L1 (325 aa)
TUFMElongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily (455 aa)
MRPL40Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family (206 aa)
MRRFRibosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) (262 aa)
MRPL52Mitochondrial ribosomal protein L52 (123 aa)
MRPL37Mitochondrial ribosomal protein L37; Belongs to the mitochondrion-specific ribosomal protein mL37 family (423 aa)
MRPL24Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family (216 aa)
MRPL21Mitochondrial ribosomal protein L21 (205 aa)
MRPL4139S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)
MRPL50Mitochondrial ribosomal protein L50 (158 aa)
RPL23LMitochondrial ribosomal protein L23 (153 aa)
MRPL47Mitochondrial ribosomal protein L47 (250 aa)
MRPS30Mitochondrial ribosomal protein S30 (439 aa)
MRPL42Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family (142 aa)
MRPL45Mitochondrial ribosomal protein L45 (306 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]