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| USP31 | Ubiquitin carboxyl-terminal hydrolase 31; May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity); Belongs to the peptidase C19 family (1352 aa) | |||
| MRPL27 | Mitochondrial ribosomal protein L27 (148 aa) | |||
| TRAF2 | TNF receptor-associated factor 2; Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes ’Lys-63’- linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin- protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein level [...] (501 aa) | |||
| MRPL4 | Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa) | |||
| MRPS9 | Mitochondrial ribosomal protein S9 (396 aa) | |||
| RPL35 | 60S ribosomal protein L35; Component of the large ribosomal subunit (123 aa) | |||
| MRPL15 | Mitochondrial ribosomal protein L15 (296 aa) | |||
| MRPL3 | Mitochondrial ribosomal protein L3 (348 aa) | |||
| MRPS5 | Mitochondrial ribosomal protein S5 (430 aa) | |||
| MRPL13 | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa) | |||
| MRPL11 | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family (192 aa) | |||
| RUVBL1 | RuvB-like 1; May be able to bind plasminogen at cell surface and enhance plasminogen activation; AAA ATPases (456 aa) | |||
| SIAH2 | E3 ubiquitin-protein ligase SIAH2; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription [...] (324 aa) | |||
| RPS2 | Ribosomal protein S2 (293 aa) | |||
| MRRF | Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) (262 aa) | |||
| SIAH1 | E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription [...] (313 aa) | |||
| MRPL24 | Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family (216 aa) | |||
| MRPL21 | Mitochondrial ribosomal protein L21 (205 aa) | |||
| MRPL9 | Mitochondrial ribosomal protein L9 (267 aa) | |||
| MRPL19 | Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family (292 aa) | |||
| SIAH3 | Seven in absentia homolog 3; Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria (269 aa) | |||
| RELA | Transcription factor p65; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kapp [...] (551 aa) | |||
| CYHR1 | Cysteine and histidine rich 1; Belongs to the CYHR1 family (362 aa) | |||
| RPL23A | 60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family (156 aa) | |||
| RPS18 | 40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; S ribosomal proteins (152 aa) | |||
| RPS20 | Ribosomal protein S20 (142 aa) | |||
